BDBM50258636 1-(3-(2-chlorophenyl)-5-sulfamoyl-1H-indole-2-carboxamido)-2,4,6-trimethylpyridinium perchlorate::1-({[5-(Aminosulfonyl)-3-(2-fluorophenyl)-1H-indol-2-yl]carbonyl}amino)-2,4,6 trimethylpyridinium perchlorate::CHEMBL513835

SMILES Cc1cc(C)[n+](NC(=O)c2[nH]c3ccc(cc3c2-c2ccccc2Cl)S(N)(=O)=O)c(C)c1

InChI Key InChIKey=TXDBKBXULDSLMV-UHFFFAOYSA-O

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50258636   

TargetCarbonic anhydrase 2(Homo sapiens (Human))
Istanbul University

Curated by ChEMBL
LigandPNGBDBM50258636(1-(3-(2-chlorophenyl)-5-sulfamoyl-1H-indole-2-carb...)
Affinity DataKi:  6.70nMAssay Description:Inhibition of human recombinant CA2 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-carbonic anhydrase 1(Mycobacterium tuberculosis)
Istanbul University

Curated by ChEMBL
LigandPNGBDBM50258636(1-(3-(2-chlorophenyl)-5-sulfamoyl-1H-indole-2-carb...)
Affinity DataKi:  25.1nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant carbonic anhydrase Rv1284 by by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase(Candida albicans (Yeast))
Istanbul University

Curated by ChEMBL
LigandPNGBDBM50258636(1-(3-(2-chlorophenyl)-5-sulfamoyl-1H-indole-2-carb...)
Affinity DataKi:  33nMAssay Description:inhibition of Candida albicans recombinant Nce103 after 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Istanbul University

Curated by ChEMBL
LigandPNGBDBM50258636(1-(3-(2-chlorophenyl)-5-sulfamoyl-1H-indole-2-carb...)
Affinity DataKi:  35.3nMAssay Description:Inhibition of human recombinant CA1 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase(Mycobacterium tuberculosis)
Istanbul University

Curated by ChEMBL
LigandPNGBDBM50258636(1-(3-(2-chlorophenyl)-5-sulfamoyl-1H-indole-2-carb...)
Affinity DataKi:  100nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant carbonic anhydrase Rv3273 by by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed