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BDBM50259535 6-(2-(difluoromethoxy)phenyl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole::CHEMBL467915

SMILES: FC(F)Oc1ccccc1C1Cc2nccn2C1

InChI Key: InChIKey=DCZFXJLVCNQIPP-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50259535   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Alpha-1A adrenergic receptor


(Homo sapiens (Human))
BDBM50259535
PNG
(6-(2-(difluoromethoxy)phenyl)-6,7-dihydro-5H-pyrro...)
Show SMILES FC(F)Oc1ccccc1C1Cc2nccn2C1
Show InChI InChI=1S/C13H12F2N2O/c14-13(15)18-11-4-2-1-3-10(11)9-7-12-16-5-6-17(12)8-9/h1-6,9,13H,7-8H2
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PC sid
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Similars

Article
PubMed
n/an/an/an/a 11n/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Agonist activity at human cloned adrenergic alpha1A receptor expressed in CHO cells assessed as calcium mobilization by FLIPR


Bioorg Med Chem Lett 19: 3118-21 (2009)

More data for this
Ligand-Target Pair