BDBM50260246 1,3-bis(4-(tert-butoxycarbonyl)benzamido)-2,4-bis(3-methoxy-4-(thiophene-2-carbonyloxy)phenyl)cyclobutane-1,3-dicarboxylic acid::CHEMBL449327
SMILES COc1cc(ccc1OC(=O)c1cccs1)C1C(NC(=O)c2ccc(NC(=O)OC(C)(C)C)cc2)(C(c2ccc(OC(=O)c3cccs3)c(OC)c2)C1(NC(=O)c1ccc(NC(=O)OC(C)(C)C)cc1)C(O)=O)C(O)=O
InChI Key InChIKey=JSLFGFBQFKCNSQ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 50260246
TargetGlucagon-like peptide 1 receptor(Rattus norvegicus)
National Center For Drug Screening
Curated by ChEMBL
National Center For Drug Screening
Curated by ChEMBL
Affinity DataKi: 1.47E+3nMAssay Description:Displacement of [125I]GLP1 from rat GLP1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetGlucagon-like peptide 1 receptor(Rattus norvegicus)
National Center For Drug Screening
Curated by ChEMBL
National Center For Drug Screening
Curated by ChEMBL
Affinity DataEC50: 371nMAssay Description:Agonist activity at rat GLP1R expressed in HEK293 cells assessed as stimulation of cAMP levels incubated for 6 hrs by multiple response element/cAMP ...More data for this Ligand-Target Pair
TargetGlucagon-like peptide 1 receptor(Rattus norvegicus)
National Center For Drug Screening
Curated by ChEMBL
National Center For Drug Screening
Curated by ChEMBL
Affinity DataEC50: 370nMAssay Description:Agonist activity at rat GLP1R expressed in HEK293 cells assessed as stimulation of cAMP levels incubated for 6 hrs by multiple response element/cAMP ...More data for this Ligand-Target Pair
TargetGlucagon-like peptide 1 receptor(Rattus norvegicus)
National Center For Drug Screening
Curated by ChEMBL
National Center For Drug Screening
Curated by ChEMBL
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of [125I]GLP1 (7-36) amide binding to rat GLP1R expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetGlucagon-like peptide 1 receptor(Rattus norvegicus)
National Center For Drug Screening
Curated by ChEMBL
National Center For Drug Screening
Curated by ChEMBL
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of [125I]GLP1 (7-36) amide binding to rat GLP1R expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetGlucagon-like peptide 1 receptor(Rattus norvegicus)
National Center For Drug Screening
Curated by ChEMBL
National Center For Drug Screening
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Inhibition of [125I]GLP1 (7-36) amide binding to rat GLP1R expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetGlucagon-like peptide 1 receptor(Rattus norvegicus)
National Center For Drug Screening
Curated by ChEMBL
National Center For Drug Screening
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Inhibition of [125I]GLP1 (7-36) amide binding to rat GLP1R expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetGlucagon-like peptide 1 receptor(Rattus norvegicus)
National Center For Drug Screening
Curated by ChEMBL
National Center For Drug Screening
Curated by ChEMBL
Affinity DataEC50: 2.73E+3nMAssay Description:Agonist activity at rat GLP1 receptor expressed in HEK293 cells assessed as cAMP releaseMore data for this Ligand-Target Pair
TargetGlucagon-like peptide 1 receptor(Rattus norvegicus)
National Center For Drug Screening
Curated by ChEMBL
National Center For Drug Screening
Curated by ChEMBL
Affinity DataEC50: >2.00E+4nMAssay Description:Agonist activity at rat GLP1R expressed in HEK293 cells assessed as stimulation of cAMP levels incubated for 6 hrs by multiple response element/cAMP ...More data for this Ligand-Target Pair
TargetGlucagon-like peptide 1 receptor(Rattus norvegicus)
National Center For Drug Screening
Curated by ChEMBL
National Center For Drug Screening
Curated by ChEMBL
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of [125I]GLP1 (7-36) amide binding to rat GLP1R expressed in HEK293 cellsMore data for this Ligand-Target Pair