BDBM50260755 (R)-2-(4-(1-(2-fluoro-6-(trifluoromethyl)benzyl)-3-(2-amino-2-phenylethyl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)benzylamino)acetic acid::CHEMBL499849
SMILES N[C@@H](Cn1c(=O)c(cn(Cc2c(F)cccc2C(F)(F)F)c1=O)-c1ccc(CNCC(O)=O)cc1)c1ccccc1
InChI Key InChIKey=BDBGKADVAYPDNK-VWLOTQADSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50260755
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 3.90E+3nMAssay Description:Binding affinity to human GnRHRMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 3.90E+3nMAssay Description:Displacement of [125I]Pro-N-Et-GnRH from human cloned GnRH receptor expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.60E+4nMAssay Description:Inhibition of recombinant CYP3A4 (unknown origin) by microtiter plate-based fluorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.60E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair