BDBM50261230 1-{2-[(1S)-(3-Dimethylaminopropionamino)-2-methylpropyl]-4-chlorophenyl}-4-[(2R)-methyl-3-(4-chlorophenyl)propionyl]piperazine::CHEMBL467588
SMILES CC(C)[C@H](NC(=O)CCN(C)C)c1cc(Cl)ccc1N1CCN(CC1)C(=O)[C@H](C)Cc1ccc(Cl)cc1
InChI Key InChIKey=FISNMOAZOFAUNZ-PIKZIKFNSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50261230
Affinity DataKi: 3.30nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 390nMAssay Description:Displacement of [125I]NDP-MSH from human MC5R expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 450nMAssay Description:Displacement of [125I]NDP-MSH from human MC3R expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 6.20E+3nMAssay Description:Displacement of [125I]NDP-MSH from human MC1R expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Antagonist activity at human MC4R expressed in CHO cells assessed as inhibition of alpha-MSH-induced cAMP production by ELISAMore data for this Ligand-Target Pair