BDBM50262279 (2S,3S)-N-((6-methoxy-3-methyl-3-(trifluoromethyl)-1,3-dihydroisobenzofuran-5-yl)methyl)-2-phenylpiperidin-3-amine::CHEMBL468830::R/S-(2S,3S)-3-(6-Methoxy-3-methyl-3-trifluoromethyl-1,3-dihydroisobenzofuran-5-yl)methylamino-2-phenylpiperidine::R/S-(2S,3S)-N-((6-methoxy-3-methyl-3-(trifluoromethyl)-1,3-dihydroisobenzofuran-5-yl)methyl)-2-phenylpiperidin-3-amine

SMILES COc1cc2COC(C)(c2cc1CN[C@H]1CCCN[C@H]1c1ccccc1)C(F)(F)F

InChI Key InChIKey=OEIZZOMBDHTIGH-QUCQDJGISA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50262279   

TargetCytochrome P450 2D6(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50262279((2S,3S)-N-((6-methoxy-3-methyl-3-(trifluoromethyl)...)
Affinity DataKi:  660nMAssay Description:Binding affinity to human CYP2D6 using bufuralol as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50262279((2S,3S)-N-((6-methoxy-3-methyl-3-(trifluoromethyl)...)
Affinity DataIC50:  0.160nMAssay Description:Displacement of [3H]spiperone from NK1 receptor in human IM9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed