BDBM50262282 11-Amino-3,3-dimethyl-12-phenyl-3,4,5,7,8,9,10,12-octahydro-2H-dibenzo[b,g][1,8]naphthyridin-1-one::CHEMBL512096

SMILES CC1(C)CC(=O)C2C(c3ccccc3)c3c(N)c4CCCCc4nc3N=C2C1

InChI Key InChIKey=GIDORMMWJGKQJZ-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50262282   

TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Laboratorio De Radicales Libres (Iqog, Csic)

Curated by ChEMBL
LigandPNGBDBM50262282(11-Amino-3,3-dimethyl-12-phenyl-3,4,5,7,8,9,10,12-...)
Affinity DataKi:  61.3nMAssay Description:Inhibition of Electrophorus electricus AChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Laboratorio De Radicales Libres (Iqog, Csic)

Curated by ChEMBL
LigandPNGBDBM50262282(11-Amino-3,3-dimethyl-12-phenyl-3,4,5,7,8,9,10,12-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human serum BuChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Laboratorio De Radicales Libres (Iqog, Csic)

Curated by ChEMBL
LigandPNGBDBM50262282(11-Amino-3,3-dimethyl-12-phenyl-3,4,5,7,8,9,10,12-...)
Affinity DataIC50:  320nMAssay Description:Inhibition of Electrophorus electricus AChE by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Laboratorio De Radicales Libres (Iqog, Csic)

Curated by ChEMBL
LigandPNGBDBM50262282(11-Amino-3,3-dimethyl-12-phenyl-3,4,5,7,8,9,10,12-...)
Affinity DataIC50:  710nMAssay Description:Inhibition of human erythrocyte AChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed