BDBM50262685 6-(4-(2-(piperidin-1-yl)ethoxy)phenyl)-3-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine::6-[4-(2-piperidin-1-ylethoxy)phenyl]-3-pyridin-4-ylpyrazolo[1,5-a]pyrimidine::CHEMBL478629::Dorsomorphin::US9040694, Dorsomorphin

SMILES: c1cc(ccc1c2cnc3c(cnn3c2)c4ccncc4)OCCN5CCCCC5

InChI Key: InChIKey=XHBVYDAKJHETMP-UHFFFAOYSA-N

Data: 1 KI  41 IC50  3 EC50

PDB links: 7 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 45 hits for monomerid = 50262685   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interferon-induced, double-stranded RNA-activated protein kinase (Human)	BDBM50262685 (CHEMBL478629 | 6-(4-(2-(piperidin-1-yl)ethoxy)phen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Bone morphogenetic protein receptor type-1A (Human)	BDBM50262685 (CHEMBL478629 | 6-(4-(2-(piperidin-1-yl)ethoxy)phen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	95	n/a	n/a	n/a	n/a	n/a	n/a
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Bone morphogenetic protein receptor type-1B (Human)	BDBM50262685 (CHEMBL478629 | 6-(4-(2-(piperidin-1-yl)ethoxy)phen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	235	n/a	n/a	n/a	n/a	n/a	n/a
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Bone morphogenetic protein 4 (Human)	BDBM50262685 (CHEMBL478629 | 6-(4-(2-(piperidin-1-yl)ethoxy)phen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	430	n/a	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM50262685 (CHEMBL478629 | 6-(4-(2-(piperidin-1-yl)ethoxy)phen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
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Ephrin type-A receptor 2 (Human)	BDBM50262685 (CHEMBL478629 | 6-(4-(2-(piperidin-1-yl)ethoxy)phen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Vascular endothelial growth factor receptor 1 (Human)	BDBM50262685 (CHEMBL478629 | 6-(4-(2-(piperidin-1-yl)ethoxy)phen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Human)	BDBM50262685 (CHEMBL478629 | 6-(4-(2-(piperidin-1-yl)ethoxy)phen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Lck (Human)	BDBM50262685 (CHEMBL478629 | 6-(4-(2-(piperidin-1-yl)ethoxy)phen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
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MAP kinase-interacting serine/threonine-protein kinase 1 (Human)	BDBM50262685 (CHEMBL478629 | 6-(4-(2-(piperidin-1-yl)ethoxy)phen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
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Ribosomal protein S6 kinase alpha-1 (Human)	BDBM50262685 (CHEMBL478629 | 6-(4-(2-(piperidin-1-yl)ethoxy)phen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Activin receptor type-1 (Human)	BDBM50262685 (CHEMBL478629 | 6-(4-(2-(piperidin-1-yl)ethoxy)phen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bone morphogenetic protein receptor type-1A (Human)	BDBM50262685 (CHEMBL478629 | 6-(4-(2-(piperidin-1-yl)ethoxy)phen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	95	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bone morphogenetic protein receptor type-2 (Human)	BDBM50262685 (CHEMBL478629 | 6-(4-(2-(piperidin-1-yl)ethoxy)phen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	74	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Activin receptor type-1 (Human)	BDBM50262685 (CHEMBL478629 | 6-(4-(2-(piperidin-1-yl)ethoxy)phen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Activin receptor type-1B (Human)	BDBM50262685 (CHEMBL478629 | 6-(4-(2-(piperidin-1-yl)ethoxy)phen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.57E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Human)	BDBM50262685 (CHEMBL478629 | 6-(4-(2-(piperidin-1-yl)ethoxy)phen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.71E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bone morphogenetic protein receptor type-1B (Human)	BDBM50262685 (CHEMBL478629 | 6-(4-(2-(piperidin-1-yl)ethoxy)phen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	235	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5'-AMP-activated protein kinase subunit beta-1 (Human)	BDBM50262685 (CHEMBL478629 | 6-(4-(2-(piperidin-1-yl)ethoxy)phen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	235	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Serine/threonine-protein kinase receptor R3 (Human)	BDBM50262685 (CHEMBL478629 | 6-(4-(2-(piperidin-1-yl)ethoxy)phen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	106	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
TGF-beta receptor type-2 (Human)	BDBM50262685 (CHEMBL478629 | 6-(4-(2-(piperidin-1-yl)ethoxy)phen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	103	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bone morphogenetic protein receptor type-1B (Human)	BDBM50262685 (CHEMBL478629 | 6-(4-(2-(piperidin-1-yl)ethoxy)phen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	467	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Activin receptor type-1 (Human)	BDBM50262685 (CHEMBL478629 | 6-(4-(2-(piperidin-1-yl)ethoxy)phen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	148	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Receptor protein serine/threonine kinase (Zebrafish)	BDBM50262685 (CHEMBL478629 | 6-(4-(2-(piperidin-1-yl)ethoxy)phen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor protein serine/threonine kinase (Zebrafish)	BDBM50262685 (CHEMBL478629 | 6-(4-(2-(piperidin-1-yl)ethoxy)phen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Activin receptor type-1 (Human)	BDBM50262685 (CHEMBL478629 | 6-(4-(2-(piperidin-1-yl)ethoxy)phen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	148	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Human)	BDBM50262685 (CHEMBL478629 | 6-(4-(2-(piperidin-1-yl)ethoxy)phen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.08E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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5'-AMP-activated protein kinase subunit beta-1/5'-AMP-activated protein kinase subunit gamma-1/Dual specificity protein kinase CLK2 (Human)	BDBM50262685 (CHEMBL478629 | 6-(4-(2-(piperidin-1-yl)ethoxy)phen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	235	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Human)	BDBM50262685 (CHEMBL478629 | 6-(4-(2-(piperidin-1-yl)ethoxy)phen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	25.1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase receptor R3 (Mouse)	BDBM50262685 (CHEMBL478629 | 6-(4-(2-(piperidin-1-yl)ethoxy)phen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	19.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Activin receptor type-1 (Mouse)	BDBM50262685 (CHEMBL478629 | 6-(4-(2-(piperidin-1-yl)ethoxy)phen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.76	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bone morphogenetic protein receptor type-1A (Mouse)	BDBM50262685 (CHEMBL478629 | 6-(4-(2-(piperidin-1-yl)ethoxy)phen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	222	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Activin receptor type-1B (Mouse)	BDBM50262685 (CHEMBL478629 | 6-(4-(2-(piperidin-1-yl)ethoxy)phen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.08E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Mouse)	BDBM50262685 (CHEMBL478629 | 6-(4-(2-(piperidin-1-yl)ethoxy)phen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.83E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor protein serine/threonine kinase (Zebrafish)	BDBM50262685 (CHEMBL478629 | 6-(4-(2-(piperidin-1-yl)ethoxy)phen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Human)	BDBM50262685 (CHEMBL478629 | 6-(4-(2-(piperidin-1-yl)ethoxy)phen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.08E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5'-AMP-activated protein kinase subunit beta-1 (Human)	BDBM50262685 (CHEMBL478629 | 6-(4-(2-(piperidin-1-yl)ethoxy)phen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	318	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Human)	BDBM50262685 (CHEMBL478629 | 6-(4-(2-(piperidin-1-yl)ethoxy)phen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	25.1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Tyrosine-protein kinase Yes (Human)	BDBM50262685 (CHEMBL478629 | 6-(4-(2-(piperidin-1-yl)ethoxy)phen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Tyrosine-protein kinase Yes (Human)	BDBM50262685 (CHEMBL478629 | 6-(4-(2-(piperidin-1-yl)ethoxy)phen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	196	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Human)	BDBM50262685 (CHEMBL478629 | 6-(4-(2-(piperidin-1-yl)ethoxy)phen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Human)	BDBM50262685 (CHEMBL478629 | 6-(4-(2-(piperidin-1-yl)ethoxy)phen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5'-AMP-activated protein kinase subunit beta-2 (Rat)	BDBM50262685 (CHEMBL478629 | 6-(4-(2-(piperidin-1-yl)ethoxy)phen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.28E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bone morphogenetic protein receptor type-2 (Human)	BDBM50262685 (CHEMBL478629 | 6-(4-(2-(piperidin-1-yl)ethoxy)phen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	74	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5'-AMP-activated protein kinase catalytic subunit alpha-2 (Human)	BDBM50262685 (CHEMBL478629 | 6-(4-(2-(piperidin-1-yl)ethoxy)phen...) Show SMILES Show InChI	GoogleScholar	UniChem		109	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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