BDBM50263043 CHEMBL501385::L-Isofagomine

SMILES OC[C@@H]1CNC[C@H](O)[C@H]1O

InChI Key InChIKey=QPYJXFZUIJOGNX-ZLUOBGJFSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50263043   

TargetLactase/phlorizin hydrolase(Rattus norvegicus)
University Of Toyama

Curated by ChEMBL
LigandPNGBDBM50263043(CHEMBL501385 | L-Isofagomine)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of rat intestinal lactase assessed as production of p-nitrophenol by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSucrase-isomaltase, intestinal(Rattus norvegicus (Rat))
University Of Toyama

Curated by ChEMBL
LigandPNGBDBM50263043(CHEMBL501385 | L-Isofagomine)
Affinity DataIC50:  3.40E+4nMAssay Description:Inhibition of rat intestinal sucrase assessed as production of p-nitrophenol at by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50263043(CHEMBL501385 | L-Isofagomine)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of human lysosomal beta-glucosidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50263043(CHEMBL501385 | L-Isofagomine)
Affinity DataIC50:  8.70E+3nMAssay Description:Inhibition of human lysosome beta-glucosidase assessed as production of 4-methylumbelliferone using 4-methylumbelliferyl beta-D-glucoside as substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-galactosidase(Bos taurus (Bovine))
University Of Toyama

Curated by ChEMBL
LigandPNGBDBM50263043(CHEMBL501385 | L-Isofagomine)
Affinity DataIC50:  8.21E+5nMAssay Description:Inhibition of bovine liver beta-galactosidase assessed as production of p-nitrophenol by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Bos taurus)
University Of Toyama

Curated by ChEMBL
LigandPNGBDBM50263043(CHEMBL501385 | L-Isofagomine)
Affinity DataIC50:  6.11E+5nMAssay Description:Inhibition of bovine liver beta-glucosidase assessed as production of 4-methylumbelliferone using 4-methylumbelliferyl beta-D-glucoside as substrate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed