BDBM50263094 (S)-3-(azetidin-2-ylmethoxy)-2-[18F]fluoropyridine::CHEMBL449437

SMILES Fc1ncccc1OC[C@@H]1CCN1

InChI Key InChIKey=GVOOYVOZPRROMP-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50263094   

TargetNeuronal acetylcholine receptor subunit alpha-4(Rat)
The Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50263094((S)-3-(azetidin-2-ylmethoxy)-2-[18F]fluoropyridine...)
Affinity DataKi:  1.33nMAssay Description:Displacement of [3H]epibatidine from rat alpha4beta2 nAChR expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-2(Rat)
The Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50263094((S)-3-(azetidin-2-ylmethoxy)-2-[18F]fluoropyridine...)
Affinity DataKi:  1.44nMAssay Description:Displacement of [3H]epibatidine from rat alpha2beta2 nAChR expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Rat)
The Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50263094((S)-3-(azetidin-2-ylmethoxy)-2-[18F]fluoropyridine...)
Affinity DataKi:  3.02nMAssay Description:Displacement of [3H]epibatidine from rat alpha3beta2 nAChR expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-2(Rat)
The Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50263094((S)-3-(azetidin-2-ylmethoxy)-2-[18F]fluoropyridine...)
Affinity DataKi:  181nMAssay Description:Displacement of [3H]epibatidine from rat alpha2beta4 nAChR expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Rat)
The Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50263094((S)-3-(azetidin-2-ylmethoxy)-2-[18F]fluoropyridine...)
Affinity DataKi:  188nMAssay Description:Displacement of [3H]epibatidine from rat alpha4beta4 nAChR expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Rat)
The Johns Hopkins University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50263094((S)-3-(azetidin-2-ylmethoxy)-2-[18F]fluoropyridine...)
Affinity DataKi:  3.68E+3nMAssay Description:Displacement of [3H]epibatidine from rat alpha3beta4 nAChR expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed