BDBM50263150 CHEMBL513892::N-(4,6-dimethyl-1-octylindolin-7-yl)-2,2-dimethylpropanamide::N-(4,6-dimethyl-1-octylindolin-7-yl)pivalamide

SMILES CCCCCCCCN1CCc2c1c(NC(=O)C(C)(C)C)c(C)cc2C

InChI Key InChIKey=SABKBGUARPNLAS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50263150   

TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Kyoto Pharmaceutical Industries

Curated by ChEMBL
LigandPNGBDBM50263150(CHEMBL513892 | N-(4,6-dimethyl-1-octylindolin-7-yl...)
Affinity DataIC50:  24nMAssay Description:Inhibition of ACAT in Japanese White rabbit liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
Kyoto Pharmaceutical Industries

Curated by ChEMBL
LigandPNGBDBM50263150(CHEMBL513892 | N-(4,6-dimethyl-1-octylindolin-7-yl...)
Affinity DataIC50:  640nMAssay Description:Inhibition of ACAT-mediated esterified cholesterol accumulation in human THP1 cells exposed to acetyl-LDL during differentiation assessed as effect o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed