BDBM50263861 1-(5-fluoro-2-(4-(methylsulfinyl)phenoxy)phenyl)-N,N-dimethylmethanamine::CHEMBL490202

SMILES: CN(C)Cc1cc(F)ccc1Oc1ccc(cc1)S(C)=O

InChI Key: InChIKey=HQGXPNMHFCEADD-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50263861   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50263861 (1-(5-fluoro-2-(4-(methylsulfinyl)phenoxy)phenyl)-N...) Show SMILES CN(C)Cc1cc(F)ccc1Oc1ccc(cc1)S(C)=O Show InChI InChI=1S/C16H18FNO2S/c1-18(2)11-12-10-13(17)4-9-16(12)20-14-5-7-15(8-6-14)21(3)19/h4-10H,11H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc Curated by ChEMBL					Assay Description Inhibition of [3H]5HT reuptake at human serotonin transporter expressed in HEK293 cells				Bioorg Med Chem Lett 18: 5303-6 (2008) Article DOI: 10.1016/j.bmcl.2008.08.040 BindingDB Entry DOI: 10.7270/Q20K28DX
					More data for this Ligand-Target Pair