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BDBM50263861 1-(5-fluoro-2-(4-(methylsulfinyl)phenoxy)phenyl)-N,N-dimethylmethanamine::CHEMBL490202

SMILES: CN(C)Cc1cc(F)ccc1Oc1ccc(cc1)S(C)=O

InChI Key: InChIKey=HQGXPNMHFCEADD-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50263861   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sodium-dependent serotonin transporter


(Homo sapiens (Human))
BDBM50263861
PNG
(1-(5-fluoro-2-(4-(methylsulfinyl)phenoxy)phenyl)-N...)
Show SMILES CN(C)Cc1cc(F)ccc1Oc1ccc(cc1)S(C)=O
Show InChI InChI=1S/C16H18FNO2S/c1-18(2)11-12-10-13(17)4-9-16(12)20-14-5-7-15(8-6-14)21(3)19/h4-10H,11H2,1-3H3
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Article
PubMed
n/an/a 600n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibition of [3H]5HT reuptake at human serotonin transporter expressed in HEK293 cells


Bioorg Med Chem Lett 18: 5303-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.040
BindingDB Entry DOI: 10.7270/Q20K28DX
More data for this
Ligand-Target Pair