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BDBM50263882 4-(2-(5-fluorobenzofuran-2-yl)vinyl)-N,N-dimethylbenzenamine::CHEMBL489978

SMILES: CN(C)c1ccc(\C=C\c2cc3cc(F)ccc3o2)cc1

InChI Key: InChIKey=VCLLMDCXDPWUSV-WEVVVXLNSA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50263882   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Beta amyloid A4 protein


(Homo sapiens (Human))
BDBM50263882
PNG
(4-(2-(5-fluorobenzofuran-2-yl)vinyl)-N,N-dimethylb...)
Show SMILES CN(C)c1ccc(\C=C\c2cc3cc(F)ccc3o2)cc1
Show InChI InChI=1S/C18H16FNO/c1-20(2)16-7-3-13(4-8-16)5-9-17-12-14-11-15(19)6-10-18(14)21-17/h3-12H,1-2H3/b9-5+
PDB
MMDB

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Similars

Article
PubMed
n/an/a 1.98E+3n/an/an/an/an/an/a



Institute of Science and Technology

Curated by ChEMBL


Assay Description
Inhibition of amyloid beta42 fibril formation by thioflavin T formation


Bioorg Med Chem Lett 18: 5591-3 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.111
BindingDB Entry DOI: 10.7270/Q20K29G7
More data for this
Ligand-Target Pair