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BDBM50264019 5-iodo-N-(4-(pyridin-2-yl)thiazol-2-yl)pyridin-2-amine::CHEMBL489282

SMILES: Ic1ccc(Nc2nc(cs2)-c2ccccn2)nc1

InChI Key: InChIKey=NMJGIAZGQDHVAH-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50264019   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Small conductance calcium-activated potassium channel protein 3 (KCa2.3)


(Homo sapiens (Human))
BDBM50264019
PNG
(5-iodo-N-(4-(pyridin-2-yl)thiazol-2-yl)pyridin-2-a...)
Show SMILES Ic1ccc(Nc2nc(cs2)-c2ccccn2)nc1
Show InChI InChI=1S/C13H9IN4S/c14-9-4-5-12(16-7-9)18-13-17-11(8-19-13)10-3-1-2-6-15-10/h1-8H,(H,16,17,18)
PDB

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Co.

Curated by ChEMBL


Assay Description
Inhibition of Kca2.3 channel expressed in HEK293 cells by thallium flux assay


Bioorg Med Chem Lett 18: 5316-9 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.023
BindingDB Entry DOI: 10.7270/Q2N87BP1
More data for this
Ligand-Target Pair