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BDBM50264397 CHEMBL522768::trans-2-(3'-Oxo-3'H-spiro[cyclohex-1,1'-isobenzofuran]-4-yl)-1H-benzoimidazole-5-carboxylic acid methyl ester

SMILES: COC(=O)c1ccc2nc([nH]c2c1)[C@H]1CC[C@@]2(CC1)OC(=O)c1ccccc21

InChI Key: InChIKey=ADTCNFSULLSHQL-MRAWUWRDSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50264397   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Neuropeptide Y receptor type 5 ( NPY Y5)


(Homo sapiens (Human))
BDBM50264397
PNG
(CHEMBL522768 | trans-2-(3'-Oxo-3'H-spiro[cyclohex-...)
Show SMILES COC(=O)c1ccc2nc([nH]c2c1)[C@H]1CC[C@@]2(CC1)OC(=O)c1ccccc21
Show InChI InChI=1S/C22H20N2O4/c1-27-20(25)14-6-7-17-18(12-14)24-19(23-17)13-8-10-22(11-9-13)16-5-3-2-4-15(16)21(26)28-22/h2-7,12-13H,8-11H2,1H3,(H,23,24)/t13-,22-
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PC cid
PC sid
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Similars

Article
PubMed
n/an/a 7.70n/an/an/an/an/an/a



Banyu Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Displacement of [125I]PYY from human recombinant NPYY5 receptor expressed in mouse LMtk cells


Bioorg Med Chem Lett 18: 4997-5001 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.021
BindingDB Entry DOI: 10.7270/Q25H7G2P
More data for this
Ligand-Target Pair