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BDBM50264489 2-(3-chlorophenoxy)-N-(4-chlorophenyl)-N-((R)-pyrrolidin-2-ylmethyl)propanamide::CHEMBL489403

SMILES: CC(Oc1cccc(Cl)c1)C(=O)N(C[C@H]1CCCN1)c1ccc(Cl)cc1

InChI Key: InChIKey=ZJDUWSIAAZAEMD-FWZWGMBYNA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50264489   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ghrelin receptor


(Homo sapiens (Human))
BDBM50264489
PNG
(2-(3-chlorophenoxy)-N-(4-chlorophenyl)-N-((R)-pyrr...)
Show SMILES CC(Oc1cccc(Cl)c1)C(=O)N(C[C@H]1CCCN1)c1ccc(Cl)cc1
Show InChI InChI=1/C20H22Cl2N2O2/c1-14(26-19-6-2-4-16(22)12-19)20(25)24(13-17-5-3-11-23-17)18-9-7-15(21)8-10-18/h2,4,6-10,12,14,17,23H,3,5,11,13H2,1H3/t14?,17-/s2
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Similars

Article
PubMed
n/an/an/an/a 120n/an/an/an/a



Bristol-Myers Squibb Co.

Curated by ChEMBL


Assay Description
Agonist activity at GHSR (unknown origin)


Bioorg Med Chem Lett 18: 5083-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.07.120
BindingDB Entry DOI: 10.7270/Q2V69JF9
More data for this
Ligand-Target Pair