BDBM50264755 4-methyl-N-(3-morpholin-4-ylphenyl)-3-(3-piperidin-4-yl-1,2-benzisoxazol-6-yl)benzamide::4-methyl-N-(3-morpholinophenyl)-3-(3-(piperidin-4-yl)benzo[d]isoxazol-6-yl)benzamide::CHEMBL485285
SMILES Cc1ccc(cc1-c1ccc2c(noc2c1)C1CCNCC1)C(=O)Nc1cccc(c1)N1CCOCC1
InChI Key InChIKey=UVUGBBNUQBSROH-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 50264755
Affinity DataKi: 1.40nMAssay Description:Displacement of fluorescent ATP competitive ligand from p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of cFMSMore data for this Ligand-Target Pair
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
Affinity DataIC50: >1.60E+4nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of LCKMore data for this Ligand-Target Pair
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of PLK1More data for this Ligand-Target Pair
Affinity DataIC50: >3.30E+4nMAssay Description:Inhibition of SGK1More data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of MEK1 by cRaf/mek/Erk cascade assayMore data for this Ligand-Target Pair
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of ErbB4More data for this Ligand-Target Pair