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BDBM50265206 1'-(4-methoxy-1H-benzo[d]imidazol-2-yl)-3H-spiro[isobenzofuran-1,4'-piperidin]-3-one::CHEMBL496345

SMILES: COc1cccc2[nH]c(nc12)N1CCC2(CC1)OC(=O)c1ccccc21

InChI Key: InChIKey=WWIGAWOVMOEZGE-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50265206   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Neuropeptide Y receptor type 5 ( NPY Y5)


(Homo sapiens (Human))
BDBM50265206
PNG
(1'-(4-methoxy-1H-benzo[d]imidazol-2-yl)-3H-spiro[i...)
Show SMILES COc1cccc2[nH]c(nc12)N1CCC2(CC1)OC(=O)c1ccccc21
Show InChI InChI=1S/C20H19N3O3/c1-25-16-8-4-7-15-17(16)22-19(21-15)23-11-9-20(10-12-23)14-6-3-2-5-13(14)18(24)26-20/h2-8H,9-12H2,1H3,(H,21,22)
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 250n/an/an/an/an/an/a



Banyu Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Binding affinity to human NPY Y5 receptor transfected in mouse LMtk cells


Bioorg Med Chem Lett 18: 5010-4 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.018
BindingDB Entry DOI: 10.7270/Q26D5STS
More data for this
Ligand-Target Pair