BDBM50265217 1-(3-fluoro-4-(4-(3-nitrobenzoyl)piperazin-1-yl)phenyl)ethanone::CHEMBL455748

SMILES CC(=O)c1ccc(N2CCN(CC2)C(=O)c2cccc(c2)[N+]([O-])=O)c(F)c1

InChI Key InChIKey=NDRPFMSUYQAUFK-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50265217   

TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50265217(1-(3-fluoro-4-(4-(3-nitrobenzoyl)piperazin-1-yl)ph...)
Affinity DataEC50:  2.45E+4nMAssay Description:Inhibition of [3H]glycine uptake at human glycine transporter 2 expressed in CHO cells by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50265217(1-(3-fluoro-4-(4-(3-nitrobenzoyl)piperazin-1-yl)ph...)
Affinity DataEC50:  3.20E+4nMAssay Description:Inhibition of [3H]glycine uptake at human glycine transporter 1 expressed in CHO cells by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed