BDBM50265375 CHEMBL496531::N-[4-[4-(2,3-Dichlorophenyl)piperazin-1-yl]butyl]3,4-dihydropyrazino[1,2-a]indol-1(2H)-one
SMILES Clc1cccc(N2CCN(CCCCN3CCn4c(cc5ccccc45)C3=O)CC2)c1Cl
InChI Key InChIKey=DGKURWUVIVQHCD-UHFFFAOYSA-N
Data 6 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50265375
Affinity DataKi: 0.105nMAssay Description:Displacement of [3H]7OH-DPAT from dopamine D3 receptor (unknown origin) expressed in Sf9 cells by scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 9.30nMAssay Description:Displacement of [3H]8OH-DPAT from 5HT1A receptor in CRL:CD(SD)BR-COBS rat hippocampus by scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 83nMAssay Description:Displacement of [3H]ketanserin from 5HT2A receptor in CRL:CD(SD)BR-COBS rat cortex by scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 122nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptor in CRL:CD(SD)BR-COBS rat striatum by scintillation spectrometryMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Siena
Curated by ChEMBL
University Of Siena
Curated by ChEMBL
Affinity DataKi: 200nMAssay Description:Binding affinity to human ERG expressed in HEK293 cells by whole cell patch clamp methodMore data for this Ligand-Target Pair
Affinity DataKi: 4.37E+3nMAssay Description:Displacement of [3H]SCH23390 from dopamine D1 receptor in CRL:CD(SD)BR-COBS rat striatum by scintillation spectrometryMore data for this Ligand-Target Pair