BDBM50265525 CHEMBL4092454

SMILES CC(NCc1nccn1C)c1cccc(O)c1

InChI Key InChIKey=IJTZJUYZQSNGMO-UHFFFAOYSA-N

Data  2 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50265525   

TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Southern California

Curated by ChEMBL
LigandPNGBDBM50265525(CHEMBL4092454)
Affinity DataKi:  155nMAssay Description:Displacement of 3H-U69593 from human KOR expressed in HEK293 cells after 90 mins by micro beta scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Southern California

Curated by ChEMBL
LigandPNGBDBM50265525(CHEMBL4092454)
Affinity DataKi:  160nMAssay Description:Displacement of 3H-U69593 from human KOR expressed in HEK293 cells after 90 mins by micro beta scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Southern California

Curated by ChEMBL
LigandPNGBDBM50265525(CHEMBL4092454)
Affinity DataEC50:  8.10E+3nMAssay Description:Agonist activity at KOR (unknown origin) expressed in HTLA cells assessed as beta-arrestin recruitment incubated overnight by Bright-Glo luminescence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Southern California

Curated by ChEMBL
LigandPNGBDBM50265525(CHEMBL4092454)
Affinity DataEC50:  530nMAssay Description:Antagonist activity at human KOR expressed in HEK293T cells coexpressing Gi assessed as Gi-mediated inhibition of cAMP production incubated for 15 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed