BDBM50265539 4-hydroxy-3-(1-methyl-1H-benzo[d]imidazol-2-yl)quinolin-2(1H)-one::CHEMBL496172

SMILES Cn1c(nc2ccccc12)-c1c(O)c2ccccc2[nH]c1=O

InChI Key InChIKey=VUWFDMHOFQDZTG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50265539   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50265539(4-hydroxy-3-(1-methyl-1H-benzo[d]imidazol-2-yl)qui...)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of human recombinant VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50265539(4-hydroxy-3-(1-methyl-1H-benzo[d]imidazol-2-yl)qui...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of human recombinant PDGFRbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50265539(4-hydroxy-3-(1-methyl-1H-benzo[d]imidazol-2-yl)qui...)
Affinity DataIC50:  7.90E+3nMAssay Description:Inhibition of human recombinant FGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed