BDBM50265574 3-(1H-benzo[d]imidazol-2-yl)-4-(4-ethyl-1-methylpiperidin-2-ylamino)quinolin-2(1H)-one::CHEMBL495984

SMILES CCC1CCN(C)C(C1)Nc1c(-c2nc3ccccc3[nH]2)c(=O)[nH]c2ccccc12

InChI Key InChIKey=TVMVUMUJXVSING-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50265574   

TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50265574(3-(1H-benzo[d]imidazol-2-yl)-4-(4-ethyl-1-methylpi...)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of human recombinant PDGFRbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50265574(3-(1H-benzo[d]imidazol-2-yl)-4-(4-ethyl-1-methylpi...)
Affinity DataIC50:  190nMAssay Description:Inhibition of human recombinant FGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50265574(3-(1H-benzo[d]imidazol-2-yl)-4-(4-ethyl-1-methylpi...)
Affinity DataIC50:  170nMAssay Description:Inhibition of human recombinant VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed