BDBM50265581 CHEMBL505036::N-{1-[1-(Morpholin-4-ylcarbonyl)-L-prolyl]piperidin-4-yl}-5-(phenylsulfonyl)-2-(trifluoromethyl)benzenesulfonamide

SMILES FC(F)(F)c1ccc(cc1S(=O)(=O)NC1CCN(CC1)C(=O)[C@@H]1CCCN1C(=O)N1CCOCC1)S(=O)(=O)c1ccccc1

InChI Key InChIKey=RIBOGOWWMKNBLE-DEOSSOPVSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50265581   

TargetSecreted frizzled-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265581(CHEMBL505036 | N-{1-[1-(Morpholin-4-ylcarbonyl)-L-...)
Affinity DataIC50:  40nMAssay Description:Binding affinity to human purified SARP2 by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene Wnt-3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50265581(CHEMBL505036 | N-{1-[1-(Morpholin-4-ylcarbonyl)-L-...)
Affinity DataEC50:  280nMAssay Description:Antagonist activity at human WNT3 expressed in human U2OS cells assessed as Wnt signaling after 16 to 18 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed