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BDBM50265643 CHEMBL498417::N'-[(3Z)-6-Methoxy-1-(2-methoxyethyl)-2-oxo-1,2-dihydro-3H-indol-3-ylidene] benzohydrazide

SMILES: COCCN1C(=O)C(=NNC(=O)c2ccccc2)c2ccc(OC)cc12

InChI Key: InChIKey=DFHPSLJKKXSEJK-JZJYNLBNSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50265643   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50265643
PNG
(CHEMBL498417 | N'-[(3Z)-6-Methoxy-1-(2-methoxyethy...)
Show SMILES COCCN1C(=O)C(=NNC(=O)c2ccccc2)c2ccc(OC)cc12
Show InChI InChI=1S/C19H19N3O4/c1-25-11-10-22-16-12-14(26-2)8-9-15(16)17(19(22)24)20-21-18(23)13-6-4-3-5-7-13/h3-9,12H,10-11H2,1-2H3,(H,21,23)/b20-17-
PDB

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PC cid
PC sid
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Article
PubMed
n/an/an/an/a>1.00E+4n/an/an/an/a



The University of Texas M.D. Anderson Cancer Center

Curated by ChEMBL


Assay Description
Inverse agonist activity at human recombinant CB1 receptor expressed CHO cells membrane by [35S]GTPgamma binding assay


J Med Chem 52: 433-44 (2009)


Article DOI: 10.1021/jm801353p
BindingDB Entry DOI: 10.7270/Q20G3M2X
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50265643
PNG
(CHEMBL498417 | N'-[(3Z)-6-Methoxy-1-(2-methoxyethy...)
Show SMILES COCCN1C(=O)C(=NNC(=O)c2ccccc2)c2ccc(OC)cc12
Show InChI InChI=1S/C19H19N3O4/c1-25-11-10-22-16-12-14(26-2)8-9-15(16)17(19(22)24)20-21-18(23)13-6-4-3-5-7-13/h3-9,12H,10-11H2,1-2H3,(H,21,23)/b20-17-
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 492n/an/an/an/a



The University of Texas M.D. Anderson Cancer Center

Curated by ChEMBL


Assay Description
Inverse agonist activity at human recombinant CB2 receptor expressed CHO cells membrane by [35S]GTPgamma binding assay


J Med Chem 52: 433-44 (2009)


Article DOI: 10.1021/jm801353p
BindingDB Entry DOI: 10.7270/Q20G3M2X
More data for this
Ligand-Target Pair