BDBM50265753 4-Amino-6,7-difluoro-3-(6-(4-methylpiperazin-1-yl)-1H-benzo[ d]imidazol-2-yl)quinolin-2(1H)-one::CHEMBL522732

SMILES CN1CCN(CC1)c1ccc2nc([nH]c2c1)-c1c(N)c2cc(F)c(F)cc2[nH]c1=O

InChI Key InChIKey=RWBSHLPMAISSHT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50265753   

TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50265753(4-Amino-6,7-difluoro-3-(6-(4-methylpiperazin-1-yl)...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human recombinant PDGFRbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50265753(4-Amino-6,7-difluoro-3-(6-(4-methylpiperazin-1-yl)...)
Affinity DataIC50:  110nMAssay Description:Inhibition of human recombinant FGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50265753(4-Amino-6,7-difluoro-3-(6-(4-methylpiperazin-1-yl)...)
Affinity DataIC50:  190nMAssay Description:Inhibition of human recombinant VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed