BDBM50265887 4-(2-(1-(2-(dimethylamino)acetyl)-5-methoxyindolin-6-ylamino)-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-N-methylthiophene-3-carboxamide::CHEMBL457548

SMILES CNC(=O)c1cscc1Nc1nc(Nc2cc3N(CCc3cc2OC)C(=O)CN(C)C)nc2[nH]ccc12

InChI Key InChIKey=ZSGVMFHELQQOIX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50265887   

TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50265887(4-(2-(1-(2-(dimethylamino)acetyl)-5-methoxyindolin...)
Affinity DataIC50:  2nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50265887(4-(2-(1-(2-(dimethylamino)acetyl)-5-methoxyindolin...)
Affinity DataIC50:  25nMAssay Description:Inhibition of IGF1R phosphorylation by cellular assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed