BDBM50265951 CHEMBL1657::TAZAROTENE::US9963439, Tazarotene::ethyl 6-[(4,4-dimethyl-3,4-dihydro-2H-thiochromen-6-yl)ethynyl]nicotinate

SMILES: CCOC(=O)c1ccc(nc1)C#Cc1ccc2SCCC(C)(C)c2c1

InChI Key: InChIKey=OGQICQVSFDPSEI-UHFFFAOYSA-N

Data: 5 IC50  3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50265951   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 3A4 (Human)	BDBM50265951 (ethyl 6-[(4,4-dimethyl-3,4-dihydro-2H-thiochromen-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.15E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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ATP-binding cassette sub-family C member 3 (Human)	BDBM50265951 (ethyl 6-[(4,4-dimethyl-3,4-dihydro-2H-thiochromen-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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ATP-binding cassette sub-family C member 2 (Human)	BDBM50265951 (ethyl 6-[(4,4-dimethyl-3,4-dihydro-2H-thiochromen-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Bile salt export pump (Human)	BDBM50265951 (ethyl 6-[(4,4-dimethyl-3,4-dihydro-2H-thiochromen-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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ATP-binding cassette sub-family C member 4 (Human)	BDBM50265951 (ethyl 6-[(4,4-dimethyl-3,4-dihydro-2H-thiochromen-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Retinoic acid receptor gamma (Human)	BDBM50265951 (ethyl 6-[(4,4-dimethyl-3,4-dihydro-2H-thiochromen-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	40	n/a	n/a	n/a	n/a
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Retinoic acid receptor alpha (Human)	BDBM50265951 (ethyl 6-[(4,4-dimethyl-3,4-dihydro-2H-thiochromen-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	63	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Retinoic acid receptor beta (Human)	BDBM50265951 (ethyl 6-[(4,4-dimethyl-3,4-dihydro-2H-thiochromen-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.800	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair