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BDBM50266013 1-(4-methoxyphenyl)-7-oxo-6-(4-(1-(pyrrolidin-1-ylmethyl)cyclopropyl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide 2,2,2-trifluoroacetate::CHEMBL451053

SMILES: COc1ccc(cc1)-n1nc(C(N)=O)c2CCN(C(=O)c12)c1ccc(cc1)C1(CN2CCCC2)CC1

InChI Key: InChIKey=VBJSHBLQAGYOJN-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50266013   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Coagulation factor X


(Homo sapiens (Human))
BDBM50266013
PNG
(1-(4-methoxyphenyl)-7-oxo-6-(4-(1-(pyrrolidin-1-yl...)
Show SMILES COc1ccc(cc1)-n1nc(C(N)=O)c2CCN(C(=O)c12)c1ccc(cc1)C1(CN2CCCC2)CC1
Show InChI InChI=1S/C28H31N5O3/c1-36-22-10-8-21(9-11-22)33-25-23(24(30-33)26(29)34)12-17-32(27(25)35)20-6-4-19(5-7-20)28(13-14-28)18-31-15-2-3-16-31/h4-11H,2-3,12-18H2,1H3,(H2,29,34)
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MMDB

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PC sid
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Similars

Article
PubMed
0.0700n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Co.

Curated by ChEMBL


Assay Description
Binding affinity to human coagulation factor 10a


Bioorg Med Chem Lett 19: 462-8 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.049
BindingDB Entry DOI: 10.7270/Q2M908HB
More data for this
Ligand-Target Pair