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BDBM50266501 CHEMBL455853::Methyl 7-(2-(2-(biphenyl-4-yl)-5-methyloxazol-4-yl)ethoxy)-2-oxochroman-3-carboxylate

SMILES: COC(=O)C1Cc2ccc(OCCc3nc(oc3C)-c3ccc(cc3)-c3ccccc3)cc2OC1=O

InChI Key: InChIKey=ZTWQZGIOXRCDQP-UHFFFAOYNA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50266501   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Peroxisome proliferator-activated receptor


(Homo sapiens (Human))
BDBM50266501
PNG
(CHEMBL455853 | Methyl 7-(2-(2-(biphenyl-4-yl)-5-me...)
Show SMILES COC(=O)C1Cc2ccc(OCCc3nc(oc3C)-c3ccc(cc3)-c3ccccc3)cc2OC1=O
Show InChI InChI=1/C29H25NO6/c1-18-25(30-27(35-18)21-10-8-20(9-11-21)19-6-4-3-5-7-19)14-15-34-23-13-12-22-16-24(28(31)33-2)29(32)36-26(22)17-23/h3-13,17,24H,14-16H2,1-2H3
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 1.12E+3n/an/an/an/a



Graduate School of the Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Agonist activity at human PPARgamma in U2OS cells by transactivation assay


Eur J Med Chem 43: 2428-35 (2008)


Article DOI: 10.1016/j.ejmech.2008.01.029
BindingDB Entry DOI: 10.7270/Q2R78F08
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50266501
PNG
(CHEMBL455853 | Methyl 7-(2-(2-(biphenyl-4-yl)-5-me...)
Show SMILES COC(=O)C1Cc2ccc(OCCc3nc(oc3C)-c3ccc(cc3)-c3ccccc3)cc2OC1=O
Show InChI InChI=1/C29H25NO6/c1-18-25(30-27(35-18)21-10-8-20(9-11-21)19-6-4-3-5-7-19)14-15-34-23-13-12-22-16-24(28(31)33-2)29(32)36-26(22)17-23/h3-13,17,24H,14-16H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 910n/an/an/an/a



Graduate School of the Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Agonist activity at human PPARalpha in U2OS cells by transactivation assay


Eur J Med Chem 43: 2428-35 (2008)


Article DOI: 10.1016/j.ejmech.2008.01.029
BindingDB Entry DOI: 10.7270/Q2R78F08
More data for this
Ligand-Target Pair