BDBM50266759 (1E,4E)-1,5-bis(4-fluorophenyl)penta-1,4-dien-3-one::1,5-bis(4-fluorophenyl)penta-1,4-dien-3-one::CHEMBL476220

SMILES Fc1ccc(\C=C\C(=O)\C=C\c2ccc(F)cc2)cc1

InChI Key InChIKey=BNHFGYIPXPENKA-YDWXAUTNSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50266759   

Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Wenzhou Medical College

Curated by ChEMBL
LigandPNGBDBM50266759((1E,4E)-1,5-bis(4-fluorophenyl)penta-1,4-dien-3-on...)
Affinity DataIC50:  507nMAssay Description:Inhibition of human 11beta-HSD1 transfected in CHOP cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Rattus norvegicus (rat))
Wenzhou Medical College

Curated by ChEMBL
LigandPNGBDBM50266759((1E,4E)-1,5-bis(4-fluorophenyl)penta-1,4-dien-3-on...)
Affinity DataIC50:  229nMAssay Description:Inhibition of 11beta-HSD1 in Sprague-Dawley rat leydig cells at 100 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Rattus norvegicus)
School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50266759((1E,4E)-1,5-bis(4-fluorophenyl)penta-1,4-dien-3-on...)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of 17beta-HSD3 in Sprague-Dawley rat testis microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Rattus norvegicus)
School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50266759((1E,4E)-1,5-bis(4-fluorophenyl)penta-1,4-dien-3-on...)
Affinity DataIC50:  100nMAssay Description:Inhibition of 17beta-HSD3 in Sprague-Dawley rat laydig cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Homo sapiens (Human))
Universiti Putra Malaysia

Curated by ChEMBL
LigandPNGBDBM50266759((1E,4E)-1,5-bis(4-fluorophenyl)penta-1,4-dien-3-on...)
Affinity DataIC50: >2.50E+5nMAssay Description:Inhibition of tyrosinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed