BDBM50267190 10-N-Demethyl-10-N-(4-(4-(pyrrolidine-1-carbonyl)-phenoxy)butan-1-yl)-galanthamine::CHEMBL473257

SMILES COc1ccc2CN(CCCCOc3ccc(cc3)C(=O)N3CCCC3)CC[C@@]34C=C[C@H](O)C[C@@H]3Oc1c24

InChI Key InChIKey=APUBMOASBJGFEG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50267190   

TargetAcetylcholinesterase(Rat)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50267190(10-N-Demethyl-10-N-(4-(4-(pyrrolidine-1-carbonyl)-...)
Affinity DataIC50: 53.8nMAssay Description:Inhibition of AChE from rat cortex homogenate by Ellmans methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50267190(10-N-Demethyl-10-N-(4-(4-(pyrrolidine-1-carbonyl)-...)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of BChE from rat serum by Ellmans methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed