BDBM50268380 (+/-)-4-oxo-N-((tans)-2-phenylcyclopropyl)spiro[chroman-2,4'-piperidine]-1'-carboxamide::4-oxo-N-((tans)-2-phenylcyclopropyl)spiro[chroman-2,4'-piperidine]-1'-carboxamide::4-oxo-N-((trans)-2-phenylcyclopropyl)spiro[chroman-2,4'-piperidine]-1'-carboxamide::CHEMBL496189

SMILES: c1ccc(cc1)[C@H]2C[C@@H]2NC(=O)N3CCC4(CC3)CC(=O)c5ccccc5O4

InChI Key: InChIKey=SWEAYHBSAXRXDZ-UHFFFAOYSA-N

Data: 15 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50268380   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 5 subunit alpha (Human)	BDBM50268380 (4-oxo-N-((tans)-2-phenylcyclopropyl)spiro[chroman-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Bifunctional epoxide hydrolase 2 (Human)	BDBM50268380 (4-oxo-N-((tans)-2-phenylcyclopropyl)spiro[chroman-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2D6 (Human)	BDBM50268380 (4-oxo-N-((tans)-2-phenylcyclopropyl)spiro[chroman-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM50268380 (4-oxo-N-((tans)-2-phenylcyclopropyl)spiro[chroman-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C9 (Human)	BDBM50268380 (4-oxo-N-((tans)-2-phenylcyclopropyl)spiro[chroman-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Bifunctional epoxide hydrolase 2 (Rat)	BDBM50268380 (4-oxo-N-((tans)-2-phenylcyclopropyl)spiro[chroman-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Bifunctional epoxide hydrolase 2 (Human)	BDBM50268380 (4-oxo-N-((tans)-2-phenylcyclopropyl)spiro[chroman-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
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Epoxide hydrolase 1 (Human)	BDBM50268380 (4-oxo-N-((tans)-2-phenylcyclopropyl)spiro[chroman-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epoxide hydrolase 1 (Human)	BDBM50268380 (4-oxo-N-((tans)-2-phenylcyclopropyl)spiro[chroman-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>100	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Human)	BDBM50268380 (4-oxo-N-((tans)-2-phenylcyclopropyl)spiro[chroman-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Human)	BDBM50268380 (4-oxo-N-((tans)-2-phenylcyclopropyl)spiro[chroman-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Human)	BDBM50268380 (4-oxo-N-((tans)-2-phenylcyclopropyl)spiro[chroman-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bifunctional epoxide hydrolase 2 (Human)	BDBM50268380 (4-oxo-N-((tans)-2-phenylcyclopropyl)spiro[chroman-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bifunctional epoxide hydrolase 2 (Rat)	BDBM50268380 (4-oxo-N-((tans)-2-phenylcyclopropyl)spiro[chroman-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 2C9 (Human)	BDBM50268380 (4-oxo-N-((tans)-2-phenylcyclopropyl)spiro[chroman-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair