BDBM50268620 6-((3'-bromo-2'-isopropoxybiphenyl-3-yl)methylamino)-9-(3-hydroxypropyl)-9H-purine-2-carbonitrile::CHEMBL497620

SMILES CC(C)Oc1c(Br)cccc1-c1cccc(CNc2nc(nc3n(CCCO)cnc23)C#N)c1

InChI Key InChIKey=YCSYUPWXKQVTEC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50268620   

TargetCathepsin B(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50268620(6-((3'-bromo-2'-isopropoxybiphenyl-3-yl)methylamin...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human liver cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
University Of California

Curated by ChEMBL
LigandPNGBDBM50268620(6-((3'-bromo-2'-isopropoxybiphenyl-3-yl)methylamin...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50268620(6-((3'-bromo-2'-isopropoxybiphenyl-3-yl)methylamin...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of human liver cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed