BDBM50268741 8-(2,6-dimethylbenzylamino)-N-(2-hydroxyethyl)-2,3-dimethylimidazo[1,2-a]pyridine-6-carboxamide::AZD-0865::CHEMBL497011

SMILES: Cc1nc2c(NCc3c(C)cccc3C)cc(cn2c1C)C(=O)NCCO

InChI Key: InChIKey=GHVIMBCFLRTFHI-UHFFFAOYSA-N

Data: 13 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50268741   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bile salt export pump (Human)	BDBM50268741 (8-(2,6-dimethylbenzylamino)-N-(2-hydroxyethyl)-2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM50268741 (8-(2,6-dimethylbenzylamino)-N-(2-hydroxyethyl)-2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2D6 (Human)	BDBM50268741 (8-(2,6-dimethylbenzylamino)-N-(2-hydroxyethyl)-2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C19 (Human)	BDBM50268741 (8-(2,6-dimethylbenzylamino)-N-(2-hydroxyethyl)-2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM50268741 (8-(2,6-dimethylbenzylamino)-N-(2-hydroxyethyl)-2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C9 (Human)	BDBM50268741 (8-(2,6-dimethylbenzylamino)-N-(2-hydroxyethyl)-2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 1A2 (Human)	BDBM50268741 (8-(2,6-dimethylbenzylamino)-N-(2-hydroxyethyl)-2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Human)	BDBM50268741 (8-(2,6-dimethylbenzylamino)-N-(2-hydroxyethyl)-2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Human)	BDBM50268741 (8-(2,6-dimethylbenzylamino)-N-(2-hydroxyethyl)-2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Human)	BDBM50268741 (8-(2,6-dimethylbenzylamino)-N-(2-hydroxyethyl)-2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Cytochrome P450 2C19 (Human)	BDBM50268741 (8-(2,6-dimethylbenzylamino)-N-(2-hydroxyethyl)-2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C9 (Human)	BDBM50268741 (8-(2,6-dimethylbenzylamino)-N-(2-hydroxyethyl)-2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 1A2 (Human)	BDBM50268741 (8-(2,6-dimethylbenzylamino)-N-(2-hydroxyethyl)-2,3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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