BDBM50268935 2-(8-(2,6-dimethylbenzylamino)-2,3-dimethylimidazo[1,2-a]pyridin-6-yl)pyridazin-3(2H)-one::CHEMBL496387

SMILES Cc1nc2c(NCc3c(C)cccc3C)cc(cn2c1C)-n1ncccc1=O

InChI Key InChIKey=LRZALAWCYDMOCP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50268935   

TargetCytochrome P450 3A4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50268935(2-(8-(2,6-dimethylbenzylamino)-2,3-dimethylimidazo...)
Affinity DataIC50:  7.20E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin) using diethoxyfluorescein as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50268935(2-(8-(2,6-dimethylbenzylamino)-2,3-dimethylimidazo...)
Affinity DataIC50:  8.50E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin) using 7-benzyloxyquinoline as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50268935(2-(8-(2,6-dimethylbenzylamino)-2,3-dimethylimidazo...)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed