BDBM50268982 1-(8-(2-chloro-4-fluorobenzylamino)-2,3-dimethylimidazo[1,2-a]pyridin-6-yl)pyridin-2(1H)-one::CHEMBL498220

SMILES Cc1nc2c(NCc3ccc(F)cc3Cl)cc(cn2c1C)-n1ccccc1=O

InChI Key InChIKey=UFWOHRJEMMPVKU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50268982   

TargetCytochrome P450 3A4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50268982(1-(8-(2-chloro-4-fluorobenzylamino)-2,3-dimethylim...)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin) using diethoxyfluorescein as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50268982(1-(8-(2-chloro-4-fluorobenzylamino)-2,3-dimethylim...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin) using 7-benzyloxyquinoline as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50268982(1-(8-(2-chloro-4-fluorobenzylamino)-2,3-dimethylim...)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed