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BDBM50269826 CHEMBL4083585

SMILES: Clc1cccc(NC(=O)c2cc(Br)ccc2OCc2ccccc2)c1

InChI Key: InChIKey=BSAHUMPLCPZMJU-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50269826   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Leucine-rich repeat serine/threonine-protein kinase 2 (LRRK2)


(Homo sapiens (Human))
BDBM50269826
PNG
(CHEMBL4083585)
Show SMILES Clc1cccc(NC(=O)c2cc(Br)ccc2OCc2ccccc2)c1
Show InChI InChI=1S/C20H15BrClNO2/c21-15-9-10-19(25-13-14-5-2-1-3-6-14)18(11-15)20(24)23-17-8-4-7-16(22)12-17/h1-12H,13H2,(H,23,24)
PDB

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Article
PubMed
n/an/a 25n/an/an/an/an/an/a



Neurodegeneration DPU

Curated by ChEMBL


Assay Description
Inhibition of LRRK2 (unknown origin) by HTRF assay


Bioorg Med Chem Lett 27: 4034-4038 (2017)


Article DOI: 10.1016/j.bmcl.2017.07.052
BindingDB Entry DOI: 10.7270/Q2MG7S1N
More data for this
Ligand-Target Pair