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BDBM50270556 1-[(Imidazolidin-2-yl)imino]-7-methylindazole hydrochloride::CHEMBL1186788::CHEMBL478356

SMILES: [#6]-c1cccc2cnn(\[#7]=[#6]-3\[#7]-[#6]-[#6]-[#7]-3)c12

InChI Key: InChIKey=MRRLJQVNGWKPQF-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50270556   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Alpha-2A adrenergic receptor


(Homo sapiens (Human))
BDBM50270556
PNG
(1-[(Imidazolidin-2-yl)imino]-7-methylindazole hydr...)
Show SMILES Cc1cccc2cnn(N=C3NCCN3)c12
Show InChI InChI=1S/C11H13N5/c1-8-3-2-4-9-7-14-16(10(8)9)15-11-12-5-6-13-11/h2-4,7H,5-6H2,1H3,(H2,12,13,15)
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 37n/an/an/an/a



Medical University of Gdansk

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant alpha2A adrenergic receptor expressed in CHO cells assessed as induction of [35S]GTPgammaS binding after 60 min...


Bioorg Med Chem 19: 321-9 (2011)

More data for this
Ligand-Target Pair
Imidazoline I1


(RAT)
BDBM50270556
PNG
(1-[(Imidazolidin-2-yl)imino]-7-methylindazole hydr...)
Show SMILES Cc1cccc2cnn(N=C3NCCN3)c12
Show InChI InChI=1S/C11H13N5/c1-8-3-2-4-9-7-14-16(10(8)9)15-11-12-5-6-13-11/h2-4,7H,5-6H2,1H3,(H2,12,13,15)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 387n/an/an/an/an/an/a



Medical University of Gda£?sk

Curated by ChEMBL


Assay Description
Displacement of [3H]clonidine from imidazoline 1 receptor in Sprague-Dawley rat kidney


J Med Chem 51: 3599-608 (2008)

More data for this
Ligand-Target Pair