BDBM50271419 CHEMBL4128252::US11225469, Compound 263
SMILES Cc1cc(C)nc(NC(=S)N2CCC(CC2)NC(=O)c2cccc(c2)C(F)(F)F)c1
InChI Key InChIKey=WLJZAFDGNKNAOM-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50271419
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Whitehead Institute For Biomedical Research
US Patent
Whitehead Institute For Biomedical Research
US Patent
Affinity DataIC50: <5.00E+3nMAssay Description:PHGDH assay buffer contained 50 mM TEA pH 8.0, 10 mM MgCl2, 0.05% BSA, and 0.01% Tween-20. PHGDH enzyme buffer consisted of assay buffer with 20 nM P...More data for this Ligand-Target Pair
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Whitehead Institute For Biomedical Research
US Patent
Whitehead Institute For Biomedical Research
US Patent
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of N-terminal His6-tagged human liver PHGDH expressed in Escherichia coli Rosetta (DE3)pLysS using 3-phosphoglycerate as substrate after 2...More data for this Ligand-Target Pair