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BDBM50271605 2-(4-(2-fluorobenzyloxy)benzyl)-3-hydroxynaphthalene-1,4-dione::CHEMBL482525

SMILES: Fc1ccccc1COc1ccc(CC2C(=O)C(=O)c3ccccc3C2=O)cc1

InChI Key: InChIKey=YOVMUZWCCKDGJQ-UHFFFAOYNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50271605   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Peroxisome proliferator-activated receptor gamma


(Rattus norvegicus)
BDBM50271605
PNG
(2-(4-(2-fluorobenzyloxy)benzyl)-3-hydroxynaphthale...)
Show SMILES Fc1ccccc1COc1ccc(CC2C(=O)C(=O)c3ccccc3C2=O)cc1
Show InChI InChI=1/C24H17FO4/c25-21-8-4-1-5-16(21)14-29-17-11-9-15(10-12-17)13-20-22(26)18-6-2-3-7-19(18)23(27)24(20)28/h1-12,20H,13-14H2
PDB
MMDB

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PC sid
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Similars

Article
PubMed
n/an/a 200n/an/an/an/an/an/a



National Institute of Pharmaceutical Education and Research

Curated by ChEMBL


Assay Description
Displacement of [3H]rosigliatzone from PPARgamma in rat adipocytes


Bioorg Med Chem Lett 18: 3192-5 (2008)


Article DOI: 10.1016/j.bmcl.2008.04.072
BindingDB Entry DOI: 10.7270/Q2J9665P
More data for this
Ligand-Target Pair