BDBM50095170 4-Methyl-pyrazole-1-carboxamidine; hydrochloride::CHEMBL452135::CHEMBL541572

SMILES Cc1cnn(c1)C(N)=N

InChI Key InChIKey=YMTPCMBHMTUVHF-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50095170   

TargetNitric oxide synthase, inducible(Mouse)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50095170(CHEMBL541572 | CHEMBL452135 | 4-Methyl-pyrazole-1-...)
Affinity DataKi:  3.00E+3nMAssay Description:Inhibition against induced Nitric Oxide Synthase(iNOS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Instituto De QuíMica MéDica

Curated by ChEMBL
LigandPNGBDBM50095170(CHEMBL541572 | CHEMBL452135 | 4-Methyl-pyrazole-1-...)
Affinity DataKi:  1.20E+4nMAssay Description:Inhibition of nNOS assessed as conversion of L-[3H]arginine to L-[3H]citrullineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Rat)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50095170(CHEMBL541572 | CHEMBL452135 | 4-Methyl-pyrazole-1-...)
Affinity DataKi:  1.20E+4nMAssay Description:Time dependent inhibition against neuronal Nitric Oxide Synthase(nNOS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50095170(CHEMBL541572 | CHEMBL452135 | 4-Methyl-pyrazole-1-...)
Affinity DataKi:  1.90E+5nMAssay Description:Inhibition against endothelial Nitric Oxide Synthase(eNOS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed