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BDBM50272263 1-[1-(4'-Fluoro-biphenyl-4-yl)-ethyl]-1H-imidazole::CHEMBL445171

SMILES: CC(c1ccc(cc1)-c1ccc(F)cc1)n1ccnc1

InChI Key: InChIKey=UPMQRSIZLKLPLH-UHFFFAOYNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50272263   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cytochrome P450 17A1


(Homo sapiens (Human))
BDBM50272263
PNG
(1-[1-(4'-Fluoro-biphenyl-4-yl)-ethyl]-1H-imidazole...)
Show SMILES CC(c1ccc(cc1)-c1ccc(F)cc1)n1ccnc1
Show InChI InChI=1/C17H15FN2/c1-13(20-11-10-19-12-20)14-2-4-15(5-3-14)16-6-8-17(18)9-7-16/h2-13H,1H3
PDB

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Similars

Article
PubMed
n/an/a 1.10E+3n/an/an/an/an/an/a



Saarland University

Curated by ChEMBL


Assay Description
Inhibition of human CYP17 expressed in Escherichia coli coexpressed with cytochrome P450 reductase


Bioorg Med Chem 16: 7715-27 (2008)


Article DOI: 10.1016/j.bmc.2008.07.011
BindingDB Entry DOI: 10.7270/Q2222TK7
More data for this
Ligand-Target Pair