BDBM50272368 4-(6-Methoxynaphthalen-2-yl)isoquinoline::CHEMBL500394

SMILES COc1ccc2cc(ccc2c1)-c1cncc2ccccc12

InChI Key InChIKey=SGBOBLSELUHWRG-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50272368   

TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50272368(4-(6-Methoxynaphthalen-2-yl)isoquinoline | CHEMBL5...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50272368(4-(6-Methoxynaphthalen-2-yl)isoquinoline | CHEMBL5...)
Affinity DataIC50:  67nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50272368(4-(6-Methoxynaphthalen-2-yl)isoquinoline | CHEMBL5...)
Affinity DataIC50:  1.62E+3nMAssay Description:Inhibition of human recombinant CYP1A2 expressed in insect microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50272368(4-(6-Methoxynaphthalen-2-yl)isoquinoline | CHEMBL5...)
Affinity DataIC50:  3.54E+3nMAssay Description:Inhibition of human recombinant CYP3A4 expressed in insect microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50272368(4-(6-Methoxynaphthalen-2-yl)isoquinoline | CHEMBL5...)
Affinity DataIC50:  1.27E+3nMAssay Description:Inhibition of human recombinant CYP2C9 expressed in insect microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50272368(4-(6-Methoxynaphthalen-2-yl)isoquinoline | CHEMBL5...)
Affinity DataIC50:  3.54E+3nMAssay Description:Inhibition of human recombinant CYP2C19 expressed in insect microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50272368(4-(6-Methoxynaphthalen-2-yl)isoquinoline | CHEMBL5...)
Affinity DataIC50:  3.31E+4nMAssay Description:Inhibition of human recombinant CYP2D6 expressed in insect microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2B6(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50272368(4-(6-Methoxynaphthalen-2-yl)isoquinoline | CHEMBL5...)
Affinity DataIC50:  1.65E+4nMAssay Description:Inhibition of human recombinant CYP2B6 expressed in insect microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed