BDBM50272428 6-Chloro-3-(3-(3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)propoxy)quinoline::CHEMBL498469

SMILES Fc1ccc(-c2noc(CCCOc3cnc4ccc(Cl)cc4c3)n2)c(Cl)c1

InChI Key InChIKey=VKLHWQFWOJTEBS-UHFFFAOYSA-N

Data  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50272428   

TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Amgen

Curated by ChEMBL
LigandPNGBDBM50272428(6-Chloro-3-(3-(3-(2-chloro-4-fluorophenyl)-1,2,4-o...)
Affinity DataEC50:  5.10nMAssay Description:Agonist activity at rat recombinant CB2 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Amgen

Curated by ChEMBL
LigandPNGBDBM50272428(6-Chloro-3-(3-(3-(2-chloro-4-fluorophenyl)-1,2,4-o...)
Affinity DataEC50:  83nMAssay Description:Agonist activity at rat recombinant CB1 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50272428(6-Chloro-3-(3-(3-(2-chloro-4-fluorophenyl)-1,2,4-o...)
Affinity DataEC50:  7.20nMAssay Description:Agonist activity at human recombinant CB2 receptor expressed in Sf9 cells by GTP-europium binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50272428(6-Chloro-3-(3-(3-(2-chloro-4-fluorophenyl)-1,2,4-o...)
Affinity DataEC50:  3.60nMAssay Description:Agonist activity at human recombinant CB2 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50272428(6-Chloro-3-(3-(3-(2-chloro-4-fluorophenyl)-1,2,4-o...)
Affinity DataEC50:  1.10E+3nMAssay Description:Agonist activity at human CB1 receptor expressed in Sf9 cells by GTP-europium binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50272428(6-Chloro-3-(3-(3-(2-chloro-4-fluorophenyl)-1,2,4-o...)
Affinity DataEC50:  990nMAssay Description:Agonist activity at human recombinant CB1 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed