BindingDB logo
myBDB logout

BDBM50272822 CHEMBL526109::N-(1H-indol-6-yl)-1-(3-(trifluoromethyl)phenyl)piperidine-4-carboxamide

SMILES: FC(F)(F)c1cccc(c1)N1CCC(CC1)C(=O)Nc1ccc2cc[nH]c2c1

InChI Key: InChIKey=XFBXQZORCMNEHX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50272822   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))
BDBM50272822
PNG
(CHEMBL526109 | N-(1H-indol-6-yl)-1-(3-(trifluorome...)
Show SMILES FC(F)(F)c1cccc(c1)N1CCC(CC1)C(=O)Nc1ccc2cc[nH]c2c1
Show InChI InChI=1S/C21H20F3N3O/c22-21(23,24)16-2-1-3-18(12-16)27-10-7-15(8-11-27)20(28)26-17-5-4-14-6-9-25-19(14)13-17/h1-6,9,12-13,15,25H,7-8,10-11H2,(H,26,28)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a>9.00E+3n/an/an/an/an/an/a



Johnson & Johnson Pharmaceutical Research and Development LLC

Curated by ChEMBL


Assay Description
Antagonist activity at human TRPV1 receptor assessed as inhibition of capsaicin-induced calcium flux by FLIPR


Bioorg Med Chem Lett 18: 4569-72 (2008)


Article DOI: 10.1016/j.bmcl.2008.07.035
BindingDB Entry DOI: 10.7270/Q2154GV5
More data for this
Ligand-Target Pair