BDBM50273136 CHEMBL455932::CHEMBL463179::{4-[2-(5-Carbamimidoyl-2-hydroxy-benzenesulfonylamino)-ethyl]-2'-methanesulfonyl-biphenyl-3-yloxy}-acetic acid; hydrochloride

SMILES CS(=O)(=O)c1ccccc1-c1ccc(CCNS(=O)(=O)c2cc(ccc2O)C(N)=N)c(OCC(O)=O)c1

InChI Key InChIKey=JFPVVWMDZGPJTA-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50273136   

TargetCoagulation factor X(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50273136(CHEMBL463179 | CHEMBL455932 | {4-[2-(5-Carbamimido...)
Affinity DataKi:  5nMAssay Description:Inhibition of human factor 10a by Dixon-plot methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50273136(CHEMBL463179 | CHEMBL455932 | {4-[2-(5-Carbamimido...)
Affinity DataKi:  5nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50273136(CHEMBL463179 | CHEMBL455932 | {4-[2-(5-Carbamimido...)
Affinity DataKi:  500nMAssay Description:Inhibition of human factor 10a by Dixon-plot methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProthrombin(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50273136(CHEMBL463179 | CHEMBL455932 | {4-[2-(5-Carbamimido...)
Affinity DataKi:  5.78E+4nMAssay Description:Inhibition of human thrombin by Dixon-plot methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed