BDBM50273289 2-Cyano-4-(1-methyl-piperidin-4-yloxy)-6-[(spiro[2.5]oct-6-ylmethyl)-amino]-pyrimidine-5-carboxylic acid benzylamide::CHEMBL458482
SMILES CN1CCC(CC1)Oc1nc(nc(NCC2CCC3(CC3)CC2)c1C(=O)NCc1ccccc1)C#N
InChI Key InChIKey=AEWVXQSQQHUKLB-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50273289
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant cathepsin S by fluorometric assayMore data for this Ligand-Target Pair
TargetProcathepsin L(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of human recombinant cathepsin L by fluorometric assayMore data for this Ligand-Target Pair