BDBM50273541 CHEMBL516312::N-(5-(4-cyanophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl)nicotinamide

SMILES: c1cc(cnc1)C(=O)Nc2c[nH]c3c2cc(cn3)c4ccc(cc4)C#N

InChI Key: InChIKey=JTSLALYXYSRPGW-UHFFFAOYSA-N

Data: 4 KI  4 IC50  12 Kd

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 24 hits for monomerid = 50273541   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
AP2-associated protein kinase 1 (Human)	BDBM50273541 (N-(5-(4-cyanophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase STK11 (Human)	BDBM50273541 (N-(5-(4-cyanophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	380	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Human)	BDBM50273541 (N-(5-(4-cyanophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	53	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase 16 (Human)	BDBM50273541 (N-(5-(4-cyanophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase receptor UFO (Human)	BDBM50273541 (N-(5-(4-cyanophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	596	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase Nek2 (Human)	BDBM50273541 (N-(5-(4-cyanophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	483	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase 3 (Human)	BDBM50273541 (N-(5-(4-cyanophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	75	n/a	n/a	n/a	n/a	n/a
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TRAF2 and NCK-interacting protein kinase (Human)	BDBM50273541 (N-(5-(4-cyanophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Serine/threonine-protein kinase STK11 (Human)	BDBM50273541 (N-(5-(4-cyanophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	380	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase pim-1 (Human)	BDBM50273541 (N-(5-(4-cyanophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Human)	BDBM50273541 (N-(5-(4-cyanophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	53	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Human)	BDBM50273541 (N-(5-(4-cyanophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Human)	BDBM50273541 (N-(5-(4-cyanophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.17E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Human)	BDBM50273541 (N-(5-(4-cyanophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Human)	BDBM50273541 (N-(5-(4-cyanophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.120	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Human)	BDBM50273541 (N-(5-(4-cyanophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	53	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Cyclin-G-associated kinase (Human)	BDBM50273541 (N-(5-(4-cyanophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.25E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Human)	BDBM50273541 (N-(5-(4-cyanophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 16 (Human)	BDBM50273541 (N-(5-(4-cyanophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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BMP-2-inducible protein kinase (Human)	BDBM50273541 (N-(5-(4-cyanophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.01E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Human)	BDBM50273541 (N-(5-(4-cyanophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		541	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-G-associated kinase (Human)	BDBM50273541 (N-(5-(4-cyanophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		1.75E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
BMP-2-inducible protein kinase (Human)	BDBM50273541 (N-(5-(4-cyanophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		4.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 16 (Human)	BDBM50273541 (N-(5-(4-cyanophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		1.19E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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