BDBM50273571 CHEMBL514409::Hesperadin::N-(2-oxo-3-(phenyl(4-(piperidin-1-ylmethyl)phenylamino)methylene)indolin-5-yl)ethanesulfonamide::TCMDC-135395

SMILES: CCS(=O)(=O)Nc1ccc2c(c1)C(C(=O)N2)/C(=N/c3ccc(cc3)CN4CCCCC4)/c5ccccc5

InChI Key: InChIKey=SGZZQKMOFHIDKW-UHFFFAOYSA-N

Data: 8 IC50  11 Kd

PDB links: 3 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 22 hits for monomerid = 50273571   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ribosomal protein S6 kinase alpha-5 (Human)	BDBM50273571 (Hesperadin | TCMDC-135395 | N-(2-oxo-3-(phenyl(4-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a
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Aurora kinase B-A (African clawed frog)	BDBM50273571 (Hesperadin | TCMDC-135395 | N-(2-oxo-3-(phenyl(4-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase A (Human)	BDBM50273571 (Hesperadin | TCMDC-135395 | N-(2-oxo-3-(phenyl(4-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase B (Human)	BDBM50273571 (Hesperadin | TCMDC-135395 | N-(2-oxo-3-(phenyl(4-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase B (Human)	BDBM50273571 (Hesperadin | TCMDC-135395 | N-(2-oxo-3-(phenyl(4-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase B (Human)	BDBM50273571 (Hesperadin | TCMDC-135395 | N-(2-oxo-3-(phenyl(4-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Fes/Fps (Human)	BDBM50273571 (Hesperadin | TCMDC-135395 | N-(2-oxo-3-(phenyl(4-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	149	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase PAK 2 (Human)	BDBM50273571 (Hesperadin | TCMDC-135395 | N-(2-oxo-3-(phenyl(4-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase BRSK2 (Human)	BDBM50273571 (Hesperadin | TCMDC-135395 | N-(2-oxo-3-(phenyl(4-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	92	n/a	n/a	n/a	n/a	n/a
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5'-AMP-activated protein kinase catalytic subunit alpha-1 (Human)	BDBM50273571 (Hesperadin | TCMDC-135395 | N-(2-oxo-3-(phenyl(4-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a
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Ribosomal protein S6 kinase alpha-4 (Human)	BDBM50273571 (Hesperadin | TCMDC-135395 | N-(2-oxo-3-(phenyl(4-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	94	n/a	n/a	n/a	n/a	n/a
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Maternal embryonic leucine zipper kinase (Human)	BDBM50273571 (Hesperadin | TCMDC-135395 | N-(2-oxo-3-(phenyl(4-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	225	n/a	n/a	n/a	n/a	n/a	n/a
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Non-receptor tyrosine-protein kinase TYK2 (Human)	BDBM50273571 (Hesperadin | TCMDC-135395 | N-(2-oxo-3-(phenyl(4-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	75	n/a	n/a	n/a	n/a	n/a
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Protein-tyrosine kinase 2-beta (Human)	BDBM50273571 (Hesperadin | TCMDC-135395 | N-(2-oxo-3-(phenyl(4-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a
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Focal adhesion kinase 1 (Human)	BDBM50273571 (Hesperadin | TCMDC-135395 | N-(2-oxo-3-(phenyl(4-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase ROS (Human)	BDBM50273571 (Hesperadin | TCMDC-135395 | N-(2-oxo-3-(phenyl(4-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	77	n/a	n/a	n/a	n/a	n/a
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Leukocyte tyrosine kinase receptor (Human)	BDBM50273571 (Hesperadin | TCMDC-135395 | N-(2-oxo-3-(phenyl(4-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase 26 (Human)	BDBM50273571 (Hesperadin | TCMDC-135395 | N-(2-oxo-3-(phenyl(4-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase 24 (Human)	BDBM50273571 (Hesperadin | TCMDC-135395 | N-(2-oxo-3-(phenyl(4-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase B (Human)	BDBM50273571 (Hesperadin | TCMDC-135395 | N-(2-oxo-3-(phenyl(4-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Aurora kinase B (Human)	BDBM50273571 (Hesperadin | TCMDC-135395 | N-(2-oxo-3-(phenyl(4-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aurora kinase B (Human)	BDBM50273571 (Hesperadin | TCMDC-135395 | N-(2-oxo-3-(phenyl(4-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
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